comparison of boric acid with clotrimazole in the treatment of recurrent or resistant vulvovaginitis caused by non-albicans species of candida

نویسندگان

nayereh khadem

a.gh. sajadi tabassi

n. ghomian

f. eftekharzadeh

چکیده

background: vulvovaginal candidiasis is one of the most common infections in gynecologic filed, and non–albicans candida species are emerging causative microorganisms. this species shows resistance to routine treatments. one of the suggested treatments is administration of vaginal suppositories of boric acid. the aim of the present study was to compare boric acid with clotrimazole in the treatment of recurrent or resistant vulvovaginitis.   methods: in a double-blind, randomized clinical trial, 90 non-pregnant women were enrolled. the patients were divided into two groups to receive; boric acid (300 mg twice a day for 2 weeks) or clotrimazole (100 mg once a day for 2 weeks) intra-vaginally. treatment responses were monitored by laboratory and clinical data.   results: treatment responses were significantly different in laboratory results for boric acid and clotrimazole groups (86.7% v 60%, p= 0.004). clinical responses (improved signs and symptoms) showed no significant differences (8.2. v 6.5, p= 0.02). drug side effects were not different in boric acid and clotrimazole groups (13.3% v 11.1%, p= 0.75).   conclusion: intra-vaginal administration of boric acid is more effective than clotrimazole in vaginal candidiasis caused by non-albicans species.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comparison of Boric Acid with Clotrimazole in the Treatment of Recurrent or Resistant Vulvovaginitis Caused by Non-Albicans Species of Candida

Background: Vulvovaginal candidiasis is one of the most common infections in gynecologic filed, and non–albicans Candida species are emerging causative microorganisms. This species shows resistance to routine treatments. One of the suggested treatments is administration of vaginal suppositories of boric acid. The aim of the present study was to compare boric acid with clotrimazole in the treatm...

متن کامل

Comparison of Boric Acid with Clotrimazole in the Treatment of Recurrent or Resistant Vulvovaginitis Caused by Non-Albicans Species of Candida

Background: Vulvovaginal candidiasis is one of the most common infections in gynecologic filed, and non–albicans Candida species are emerging causative microorganisms. This species shows resistance to routine treatments. One of the suggested treatments is administration of vaginal suppositories of boric acid. The aim of the present study was to compare boric acid with clotrimazole in the treatm...

متن کامل

study of cohesive devices in the textbook of english for the students of apsychology by rastegarpour

this study investigates the cohesive devices used in the textbook of english for the students of psychology. the research questions and hypotheses in the present study are based on what frequency and distribution of grammatical and lexical cohesive devices are. then, to answer the questions all grammatical and lexical cohesive devices in reading comprehension passages from 6 units of 21units th...

comparison of catalytic activity of heteropoly compounds in the synthesis of bis(indolyl)alkanes.

heteropoly acids (hpa) and their salts have advantages as catalysts which make them both economically and environmentally attractive, strong br?nsted acidity, exhibiting fast reversible multi-electron redox transformations under rather mild conditions, very high solubility in polar solvents, fairly high thermal stability in the solid states, and efficient oxidizing ability, so that they are imp...

15 صفحه اول

Fluconazole-resistant Candida albicans vulvovaginitis.

OBJECTIVE As a result of high recurrence rates of Candida albicans vaginitis, successful suppressive fluconazole is widely used, and drug resistance is considered rare. We report increased occurrence of secondary fluconazole resistance, analysis of risk factors thereof, and describe management of fluconazole-refractory vaginitis. METHODS Patients referred to the Vaginitis Clinic at Wayne Stat...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of medical sciences

جلد ۳۳، شماره ۴، صفحات ۲۲۶-۰

کلمات کلیدی

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023